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Deprescribing Medications for Older Adults

Friday, January 19, 2018 2:22:42 AM America/Los_Angeles

Many older adults take too many prescription drugs or take them at too-high doses. Prescriptions started long ago to treat temporary medical conditions somehow never get stopped. Other preventive drugs may offer little to no benefit after a certain age and bring unacceptable side effects for older users.

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FDA Approves Drug for Certain Advanced or Metastatic Breast Cancers

Friday, January 19, 2018 2:20:36 AM America/Los_Angeles

Officials with the FDA have approved abemaciclib (Verzenio, Eli Lilly), for the treatment of adults with certain advanced or metastatic breast cancer. The drug is indicated for patients who have hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer that has progressed after endocrine therapy.

The drug is approved to be given in combination with an endocrine therapy, called fulvestrant. It can also be given as a stand-alone therapy, if patients were previously treated with endocrine therapy and chemotherapy after the cancer had spread.

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Does Low-Dose Aspirin Reduce Risk of Breast Cancer?

Friday, January 19, 2018 2:18:15 AM America/Los_Angeles

Low-dose aspirin may help women reduce their risk of developing breast cancer, a new study published in Breast Cancer Research has suggested.1 Overall, regular low-dose aspirin use (81 mg) was tied to a 16% lower risk of breast cancer in women when taken at least 3 times per week.
 
The study, led by Leslie Bernstein PhD, included women who worked in California public schools. Participants completed a baseline questionnaire from 1995-1996 based on family history of cancer and other conditions, use of NSAIDs, menstrual and reproductive history, self-reported weight and height, living environment, diet, alcohol use, and physical activity. From 2005-2006, 57,164 participants provided updated information, and 1457 of these participants developed invasive breast cancer before January 2013.

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